Growth hormone’s role in fertility – both female and male – has been well documented. Successful management of male and female infertility has been employed over time. In the examination of female infertility, we find that GH manufacturing takes place in both the pituitary gland and the ovaries. It is there, in the ovaries, where it binds to growth hormone receptors found on granulosa, thecal, and luteal cells. This promotes the process of gametogenesis (where cells undergo meiosis – cell division – to form gametes) and steroidogenesis (the process converting cholesterol into steroid hormones).
Growth hormone production stimulates the liver to secrete insulin growth factor 1 (IGF-1). This is essential because GH, IGF-1, and GHRH (growth hormone releasing hormone) increase the ovaries sensitivity to gonadotropin stimulation to increase follicular development. Growth hormone also helps to enhance the aromatase activity that converts androgen hormones into estrogen hormones in females. GH, IGF-1, and IGF-2 also affect the maturation process of the follicle and the gamete (mature cell).
Oocytes (eggs) taken from the follicles of women with normal GH levels have been shown to be more fertile than those with low growth hormone production. The role of GH in the process of accelerating egg maturation and ovarian stimulation is well documented.
What is Human Growth Hormone?
Human growth hormone (somatropin) is the bioidentical version of growth hormone (somatotropin) – a vital chemical messenger produced by the pituitary gland. The adrenal gland and ovaries provide a small amount of GH to the body, as well.
Since growth hormone is often considered to be one of the body’s most essential chemicals, the use of somatropin is crucial when a shortage or deficiency is diagnosed. Unlike synthetic hormones supplements that require conversion in the body before their properties can be utilized, HGH is a biological twin to growth hormone. Its molecular structure is identical to the 191 chain amino acid peptide that occurs naturally in the body so it can be assimilated and used immediately without any conversion process.
Infertility treatment at Kingsberg medical is it the real chance for many people. Hormone replacement therapy specialists prescribe HGH injections to women and men with adult growth hormone deficiency to improve physiological functions. Human growth hormone also helps with weight loss, metabolism, muscle and bone development, mood, and brain functions.
Human growth hormone therapy is available as an injectable medication. Its molecular structure is too large to pass through the skin or nasal or oral membranes. It cannot be taken as a pill, spray, drop, patch, or cream. Products that call themselves HGH that are not prescription injectables are not real human growth hormones.
Can HGH Cure Infertility?
HGH is not the “cure” for infertility, although it may be the answer many women need. It has specific uses for certain protocols when it comes to treating fertility issues in females. Human growth hormone therapy has been used successfully with hMG (human menopausal gonadotropin – combining luteinizing hormone and follicle stimulating hormone to stimulate production of multiple eggs in a cycle) and hCG (human chorionic gonadotropin – to trigger ovarian release of the mature egg) to induce ovulation and improve follicle growth in women with hypogonadotropic hypogonadism. The benefits of using HGH in this way reduce the amount of gonadotropin and the duration of hMG treatment. Success rates have been increased with this protocol.
Women who have been poor responders to other treatments may receive benefits from HGH supplementation. Human growth hormone has not shown benefits in women with no prior history of poor response to traditional IVF stimulation protocols.
There may also be an estrogen-mediated or independent effect of uterine size resulting from human growth hormone therapy use. The use of HGH therapy for infertility requires a close collaboration between hormone and fertility specialists.
Aside from the direct benefits shown for the treatment of fertility issues, HGH helps women lose weight, improve sleep quality and duration, and achieve a positive outlook. The emotional well-being provided by human growth hormone can induce a relaxation that can also lead to successful pregnancy, and higher levels of HGH in the bloodstream reduce the amount of cortisol, the stress hormone. High cortisol levels can keep a woman feeling tense, especially crucial at this time when she needs to relax to allow her body to respond to treatments.
A hormone replacement therapy specialist can provide further insight into the benefits of growth hormone in the management of female infertility.